I’m sure many of you have heard of antioxidants- we get them in superfoods we want them in all of our anti-aging skin serums. Antioxidants improve radiance in your skin, stop inflammation, maintain youthful energy, and fight the damaging effects of life, stress, even processes in the body like metabolism that cause aging. Antioxidants are basically everything amazing. They help reduce the negative effects of aging on your body by fighting free radicals that attack cells and break down DNA in our bodies.

The purpose of beauty bio-hacking is about discovering how we can take anti-aging in our skin, mind and body and to a deeper level than eating a few berries and putting on an overpriced anti-aging skin serum. Exploring the use of vitamins antioxidants, minerals, and nootropics we can get control at the cellular level to maintain our bodies and live our healthiest happiest lives.

I’ve been thinking a lot about what fundamental supplements more people need to be aware of. The first thing that came to mind was PQQ. Through my own research, I discovered PQQ and since I began taking it I really believe it is an essential nutrient. As a powerful antioxidant PQQ helps your maintain cellular function on all levels and promotes happy healthy cells through out the body. The more PQQ you have in your system, the better protected your brain cells even have from free radical damage!

We want amazing skin but we also want to feel great and fully alive! Having the proper nutrients to fight off stress and feed our bodies is essential.

I know many many (majority) of people are still new to nootropics but that’s fine that’s fine, it just makes us pioneers. Stick with me because we are going to discover some amazing scientifically proven foods, suppliments, and nootropics to optimize our health.

PQQ has quickly become one of my favorite staple supplements because it does so many health benefits for the human body that too few know about! Like I said, I really believe PQQ intake is foundational in any anti-aging. Human studies can link systemic effects in the body, such as an increase in mitochondrial function, to local effects, like increased nerve growth. PQQ and enhanced mitochondria related functions and cognitive performance go together- they are essential for each other!

I wanted to share all of my research to help you decide if PQQ is a supplement for you. In this article over how it helps our bodies, mind and mood.

Remember these products are potent so discussing it with a doctor or medical professional is strongly advised.

Let’s dive in…

Benefits of PQQ as a natural Nootropic

Nootropic supplements are natural or synthetic substances that improve cognitive function, such as creativity, memory, and motivation. They can have amazing memory-boosting powers!

PQQ works as an effective nootropic that can provide you with more energy, enthusiasm, and stamina to tackle everyday life. This can benefit all lifestyles if you are someone who has trouble keeping track of things, experience a lack of interest in your work or at home, or needs help to stay motivated.

PQQ is safe for consumption by pregnant women and nursing mothers- with no risk of toxicity. In fact, studies have found that taking a dose every day during pregnancy can help the brain develop better.

Benefits of Pyrroloquinoline Quinone (PQQ) as a Micronutrient for brain health

Pyrroloquinoline Quinone PQQ is not what most people think it is- just a potent antioxidant. In fact, many people don’t even know what it is and where it comes from. I guess you can call it an “exotic supplement” known primarily in bio-hacking circles. I wanted to bring attention to PQQ as one of the foundational supplements because so few know or understand and the powerful anti-aging benefits.

Nootropic supplements have changed my life! PQQ was one of the first natural supplements I began taking and my only regret is that I didn’t start it sooner. The apparent changes were slow to develop, like most nootropics, but as time progressed I see how much stability PQQ has introduced into my overall health and cognitive functions.

PQQ supplementation is very important for human health since it acts as fuel for the energy production processes in mitochondria to help regulate cellular metabolism. PQQ influences energy-related metabolism to increase cellular energy production. This in turn leads to better cognitive performance in brain cells, reduced inflammation, anti-aging, more energy, enhanced memory, and even improved sleep quality.

PQQ is Vitamin-like but classified as a nootropic.

All vitamins are nootropics, but not all nootropics are vitamins. 

The brain needs the same enzyme cofactors as other parts of the body, yet food alone can be insufficient when it comes to the full range of nutrients needed for the human body to function especially since the body is unable to produce PQQ on it’s own.

Since the brain needs extra support to function at optimal levels, taking PQQ with its high antioxidant potential can have major cognitive benefits, from increasing the efficiency of brain activity to reduced brain fog.

How PQQ improves cognitive health

The goal of cognitive health is to support an individual’s ability to think, remember, and process information. Free radicals cause damage to cells, and since brain cells are more sensitive than others, a lack of protection can lead to impaired cognitive function over time. Maintaining brain tissue and promoting new brain cells is important for healthy aging. Dietary PQQ exposure helps improve mental energy by reducing mitochondrial dysfunction. Since PQQ helps the body neutralize free radicals, it fights age-related cognitive decline.

Decreasing stress levels is also one way that supplementing with this nutrient also reduces stress hormone cortisol, which may be able to provide relief for people who suffer from anxiety or depression symptoms related to their mental health. Less cortisol can improve sleep quality. Improve sleep quality we improve overall all cognitive function and healing in the body.

The positive effects of PQQ can also be seen as improved cardiovascular health overall, which may contribute to its ability to work against diseases such as Parkinson’s or Alzheimer.

How does PQQ help memory and nerve cells?

Since PQQ is such a potent antioxidant that protects against inflammation-induced oxidative stress. PQQ antioxidant potential extends to help prevent oxidative stress to the brain cells and protects them from damage, which can lead to improved memory function. clinical studies show PQQ also improves nerve growth factor (NGF) within the nerve cells.

PQQ increases Nerve Growth Factor

Pyrroloquinoline quinone PQQ alters nerve growth factor and promotes more neuronal growth which is a vital part of the maintaining the nervous system and other bodily functions. It has been found to have an effect on concentration, memory, learning ability (among many others) in both animal studies and humans subjects alike.

Improving nerve growth factor (NGF), Pyrroloquinoline quinone PQQ helps prevent cognitive decline by helping to kill neurons that are not functioning properly.

Other supplements that target nerve growth factor include:

– Acetyl L Carnitine

– Astaxanthin

– Choline Bitartrate

What is Pyrroloquinoline Quinone PQQ and what does it do to our body?

What is PQQ exactly? To be precise, it is a micronutrient and nootropic that offers huge antioxidant potential. PQQ plays a critical role in reducing mitochondrial dysfunction- which is a cornerstone to healthy aging. PQQ is a cofactor, or enzyme booster, for the Redox process (Reduction Oxidation), which has numerous significant effects on antioxidation.

A study conducted by Yasue Yamada (2020) verified the physiological effects of PQQ in the human body, including growth promotion of new mitochondria, neuroprotection to improve cognitive function, stimulation of the mitochondria, and antioxidation. It was concluded that PQQ supplementation resulted in improved learning ability, boosts memory as an anti-aging nutrient that again protects nerve cells from damage. According to a study published in the Journal of Food and Nutrition, PPQ also reduces inflammation by inhibiting inflammatory cytokines production. (Hongyun Zhang, 2020)

Mitochondria are the powerhouse for energy production throughout your cells- but it declines as we age. Since a mitochondrial function can be improved by PQQ, and improvements in mitochondrial function can lead to increases in ATP production, PPQ can slow down the aging process and fight neurodegenerative diseases.

Mitochondrial function in health

In your quest for longevity and to live an optimal life, an important component of anti-aging is mitigating mitochondrial dysfunction. As we know now, taking PQQ plays a key role in the health of our cells. Cells require energy and our mitochondria produce the energy for cells to do their job. Mitochondria are the powerhouse for energy production throughout your body – but it declines as we age.

Mitochondrial dysfunction is the main precursor to accelerate the aging process in humans. With age, our function declines to less than 50%. Mitochondrial dysfunction also causes oxidative stress and DNA damage, which are both major contributors to aging. PQQ can mitigate damage and even promote regrowth!

What is mitochondrial-related metabolism?

Since mitochondria are the powerhouse of our cells it has a central role in cellular metabolism which includes processes such as fatty acid synthesis, Kreb’s cycle, electron transport chain, oxidative phosphorylation, and reduction oxidation.

PQQ dietary supplements improve mitochondrial-related metabolism by increasing ATP production through improving oxygen consumption. Improving Oxygen consumption within the body is always a good thing because it helps your body to get rid of more free radicals.

If you are someone who struggles with weight loss, lethargy, fatigue, jaundice, or seizures, you are exposed to a metabolic disorder the addition of PQQ supplementation or dietary PQQ would be extremely beneficial (Xuan Xu, 2020). 

What is Mitochondrial Biogenesis?

PQQ is the one of the few nutrients to help stimulate new mitochondria by creating more of these stem cells and it also boosts mitochondrial function by improving ATP production.(Hongyun, Zhang) PQQ stimulates mitochondrial biogenesis by increasing the number of mitochondria present in cells. It does this through two different pathways: PGC-alpha and NO synthase (NOS).

other supplements that stimulate mitochondrial biogenesis include:

– CoQ

– Carnitine


Oxidative stress effects on the body

Oxidative stress happens naturally in the body and is a normal process that can be kept in check with enough PQQ. However, when your antioxidant defense system starts to decline due to age or environmental factors, oxidative stress becomes dangerous for the body and tissue damage will occur.

Effects of oxidative stress include damage to mitochondria, DNA, and proteins. This damages the cellular machinery necessary for life which can lead to a number of health problems. The effects from oxidative stress accumulate over one’s lifespan until they eventually become fatal. Normal processes in the body that create Oxidative stress include:

– Mitochondria respiration that uses oxygen as fuel to create energy.

– The body’s immune system, which defends against harmful bacteria and viruses. The stress of this process can lead to inflammation or chronic illnesses like cancer.

– Certain foods turn into oxidative radicals when they are metabolized by our bodies including sugar molecules in fruit

How PQQ Reduces Inflammation

Research shows that Pyrroloquinoline Quinone PQQ has anti-inflammation effects on the body and can tackle multiple symptoms of inflammation in the body at the same time, thus reducing the risk of significant decreases in multiple inflammatory ailments. This extends to pain occurring by touching an affected area, redness in the skin, swelling, heat due to increased blood flow, difficulty moving a joint, smelling, or breathing.

Inflammation is caused by an accumulation of inflammatory cells and their secretions that lead to the typical symptoms. PQQ has been found to inhibit the production of inflammatory cells and their secretions, which reduces inflammation. PQQ also reduces oxidative stress by scavenging free radicals and reversing peroxide-induced damage in tissues.

Inflammation is the root cause of so many ailments. It can be caused by any number of things, including genetics, poor diet choices, lack of exercise or even stress.

PQQ supplements are clinically proven to reduce stress and help calm down overactive immune cells that cause chronic inflammation by promoting a healthy balance of T-cells or white blood cells known as lymphocytes.

Where to get dietary Pyrroloquinoline Quinone PQQ

Hopefully, by now you feel confident in PQQ’s benefits. Now is the challenge to finding high-quality nootropic.

Pyrroloquinoline Quinone (PPQ) is found naturally in soil, a variety of fruits such as soybeans, spinach, and kiwi, as well as in human breast milk. PQQ in foods is not always in a form that can be easily assimilated by the body.

For PQQ to work effectively as an antioxidant and nootropic, it needs to be converted into its bioactive form (Pyrroloquinoline Quinone) which is found primarily in animal products such as liver and kidney or other supplements.

Bioactive supplements are micronutrients that can be taken in supplement form and their bioavailability is high enough to provide the same benefits as if they were consumed through a natural or organic diet.

Dietary supplements such as PQQ are generally more effective than PPQ rich functional foods because it has been shown that our intestines can’t always convert PQA into PQQ efficiently, which makes consuming foods with PQQ Pyrroloquinoline Quinone difficult for many people.

Best PQQ Nootropics to buy

You should be taking PQQ on a daily basis. PQQ doses range from 40mg to 1000mg per day, so you’ll need to consult with your doctor or a medical professional to provide medical advice on proper dosage for you.

Finding Bioactive supplements is not so simple because many brands don’t publish or test the potency. PQQ works better when combined with other vitamins and minerals, so make sure you are taking a good multi-vitamin in addition to PQQ.

Best Brands for PQQ are:

  • Jarrow ##mg
  • Amazon
  • Noo
  • Noook
  • dfksdf

In conclusion

When we think of beauty ultimately our mind, mood, our aura or energy are tied together with physical feature to define what makes us beautiful. We all have a unique We want to be using the most potent When I think about how we can increase and o help our bodies protect and rejuvenate.

Pyrroloquinoline quinone has been identified as a “longevity vitamin” not essential for immediate survival, but necessary for long-term health. Taking PQQ on a daily basis is recommended to protect your body from the ravages of aging and disease. One study found that pyrroloquinoline quinone was able to “significantly arrest” human cell senescence, or the deterioration associated with age-related diseases. If you’re feeling sluggish or tired during the day, PQQ can help give you more energy by promoting cellular respiration and increasing mitochondrial activity-the process through which cells convert nutrients into usable energy sources like ATP (adenosine triphosphate).

Not only does it have effective anti-aging and antioxidation effects, but it also acts as a nootropic for improving cognitive health. Dietary PQQ exposure benefits encompass improvements in learning ability, boosting memory, improving brain function, protecting nerve cells from damage, reducing inflammation, improving sleep quality, and increasing healthy cholesterol levels. The increase in energy that you experience will allow you to live your best life each and every day while reaping countless benefits to your overall health.  

There are not many nutrients out there that promote healthy energy and improve cognitive functioning, increase memory retention and promote positive moods- which are all integral parts of good health at any age. Many people have taken notice of its neuroprotective properties. Don’t miss out on the wonderful restorative effects of PQQ!

is also an antioxidant which helps neutralize free radicals in cells , so it can be used for both prevention as well as treatment of cellular oxidation damage .


  1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994848/
  2. https://pubmed.ncbi.nlm.nih.gov/31860387/
  3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369269/
  4. https://pubmed.ncbi.nlm.nih.gov/32073012/

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